Maternal effects on mouse brain weight

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Maternal effects on mouse brain weight.

When BALB/cCF mice were crossed reciprocally with 4 other inbred strains, adult brain weights averaged 21.0 mg heavier for hybrid offspring with a BALB mother than those with a BALB father. Reciprocal backcrosses to BALB revealed that this effect was a consequence of the BALB maternal environment, not cytoplasmic or sex chromosomal influences. These findings demonstrate that BALB mice have heav...

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Distinct Effects of Estrogen on Mouse Maternal Behavior: The Contribution of Estrogen Synthesis in the Brain

Estrogen surge following progesterone withdrawal at parturition plays an important role in initiating maternal behavior in various rodent species. Systemic estrogen treatment shortens the latency to onset of maternal behavior in nulliparous female rats that have not experienced parturition. In contrast, nulliparous laboratory mice show rapid onset of maternal behavior without estrogen treatment...

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Effects of Maternal Factors on Birth Weight in Japan

OBJECTIVE We investigated the possible factors related to the birth weight (BW) using the Japanese perinatal database. METHODS The live infants born at 37 to 41 weeks of gestation were enrolled in this study. Cases with diabetic pregnancy, preeclampsia, an anomalous fetus, and a fetus with chromosomal abnormalities were excluded. A multiple regression analysis for confounding factors and an a...

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P30: Effects of Hemin on Ca2+Influx in Neurons of C57BL/6 Mouse Brain

Excitotoxicity results in a significant increase in Ca2+ influx; essentially from open N-Methyl-D-aspartate receptors (NMDARs) channels that cause a secondary rise in the intracellular Ca2+ concentration. It is correlated with neuronal death induced by Ca2+ overload. Dysfunction of NMDARs is associated with excitotoxic neuronal death in neurodegenerative disorders. In this study, the effects of...

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ژورنال

عنوان ژورنال: Developmental Brain Research

سال: 1983

ISSN: 0165-3806

DOI: 10.1016/0165-3806(83)90054-8